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Necrosis

Necrosis is the death of body tissue. It occurs when too little blood flows to the tissue. This can be from injury, radiation, or chemicals. Necrosis cannot be reversed.

When large areas of tissue die due to a lack of blood supply, the condition is called gangrene.

References

Kumar V, Abbas AK, Aster JC. Cellular responses to stress and toxic insults: adaptation, injury, and death. In: Kumar V, Abbas AK, Aster JC, eds. Robbins and Cotran Pathologic Basis of Disease. 9th ed. Philadelphia, PA: Elsevier Saunders; 2015:chap 2.

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    • Meningococcemia on the calves

      Meningococcemia on the calves

      illustration

    • Meningococcemia on the leg

      Meningococcemia on the leg

      illustration

    • Meningococcemia associated purpura

      Meningococcemia associated purpura

      illustration

    • Necrosis of the toes

      Necrosis of the toes

      illustration

      • Meningococcemia on the calves

        Meningococcemia on the calves

        illustration

      • Meningococcemia on the leg

        Meningococcemia on the leg

        illustration

      • Meningococcemia associated purpura

        Meningococcemia associated purpura

        illustration

      • Necrosis of the toes

        Necrosis of the toes

        illustration

       

      Review Date: 8/5/2017

      Reviewed By: Frank A. Greco, MD, PhD, Director, Biophysical Laboratory, Edith Nourse Rogers Memorial Hospital, Bedford, MA. Review provided by VeriMed Healthcare Network. Also reviewed by David Zieve, MD, MHA, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team.

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